BDBM288623 (E)-3-(3,5-difluoro-4-((1S,3R/1R,3S)-2-(2-fluoro-2-methylpropyl)-3-methyl-6-(2-(methylamino)-2-oxoethoxy)-1,2,3,4-tetrahydroisoquinolin-1-yl)phenyl)acrylic acid::US10087191, Example 32
SMILES CNC(=O)COc1ccc2C(N(CC(C)(C)F)C(C)Cc2c1)c1c(F)cc(\C=C\C(O)=O)cc1F
InChI Key InChIKey=HGYWNRSMJDSIRM-VMPITWQZSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 288623
Affinity DataIC50: 1.45nMAssay Description:The compounds of the present invention have an inhibition effect on the binding of E (estrogen) to ER (estrogen receptor), thereby blocking the bindi...More data for this Ligand-Target Pair