BDBM28884 2-[(5Z)-4-oxo-5-({1-phenyl-3-[4-(piperidine-1-sulfonyl)phenyl]-1H-pyrazol-4-yl}methylidene)-2-sulfanylidene-1,3-thiazolidin-3-yl]ethane-1-sulfonic acid::rhodanine derivative, 43

SMILES OS(=O)(=O)CCN1C(=S)S\C(=C/c2cn(nc2-c2ccc(cc2)S(=O)(=O)N2CCCCC2)-c2ccccc2)C1=O

InChI Key InChIKey=CULPOYNTOOOYIX-QJOMJCCJSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 28884   

TargetLethal factor(Bacillus anthracis)
Burnham Institute For Medical Research

LigandPNGBDBM28884(2-[(5Z)-4-oxo-5-({1-phenyl-3-[4-(piperidine-1-sulf...)
Affinity DataIC50:  2.07E+3nMAssay Description:The fluorescence peptide cleavage assay was performed in a 96-well plate in which each reaction mixture contained MAPKKide, LF (List Biological Labor...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBotulinum neurotoxin type A2 [1-425](Clostridium botulinum)
Burnham Institute For Medical Research

LigandPNGBDBM28884(2-[(5Z)-4-oxo-5-({1-phenyl-3-[4-(piperidine-1-sulf...)
Affinity DataIC50:  2.01E+4nMAssay Description:The fluorescence peptide cleavage assay was performed in a 96-well plates in which each reaction mixture contained SNAPtide, BoNT /A (List Biological...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein phosphatase 3(Homo sapiens (Human))
Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM28884(2-[(5Z)-4-oxo-5-({1-phenyl-3-[4-(piperidine-1-sulf...)
Affinity DataIC50:  270nMAssay Description:Inhibition of recombinant vaccina H1-related phosphataseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 1(Homo sapiens (Human))
Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM28884(2-[(5Z)-4-oxo-5-({1-phenyl-3-[4-(piperidine-1-sulf...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant Cdc25aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM28884(2-[(5Z)-4-oxo-5-({1-phenyl-3-[4-(piperidine-1-sulf...)
Affinity DataIC50:  2.20E+3nMAssay Description:Inhibition of recombinant PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 7(Homo sapiens (Human))
Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM28884(2-[(5Z)-4-oxo-5-({1-phenyl-3-[4-(piperidine-1-sulf...)
Affinity DataIC50:  2.40E+3nMAssay Description:Inhibition of recombinant HePTPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein phosphatase 1(Homo sapiens (Human))
Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM28884(2-[(5Z)-4-oxo-5-({1-phenyl-3-[4-(piperidine-1-sulf...)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibition of recombinant MKP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase C(Homo sapiens (Human))
Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM28884(2-[(5Z)-4-oxo-5-({1-phenyl-3-[4-(piperidine-1-sulf...)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of recombinant CD45More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed