BDBM289034 6-chloro-3-(3-(4-chloro-3,5-dimethylphenoxy)propyl)-N-((2-(1-(3-methylbenzyl)-1H-pyrrole-2-carboxamido)ethyl)sulfonyl)-1H-indole-2-carboxamide::US10093640, Example 245::US10844032, Example 245
SMILES Cc1cccc(Cn2cccc2C(=O)NCCS(=O)(=O)NC(=O)c2[nH]c3cc(Cl)ccc3c2CCCOc2cc(C)c(Cl)c(C)c2)c1
InChI Key InChIKey=MJCGSMUWOAGWEJ-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 289034
TargetInduced myeloid leukemia cell differentiation protein Mcl-1 [172-327](Homo sapiens (Human))
Vanderbilt University
US Patent
Vanderbilt University
US Patent
Affinity DataKi: 200nMAssay Description:The assay was run using a fluorescein isothiocyanate-labeled BH3 peptide derived from Bak (FITC-AHx-GQVGRQLAIIGDDINR-NH2) that was purchased from Gen...More data for this Ligand-Target Pair
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Novartis
US Patent
Novartis
US Patent
Affinity DataIC50: 200nMpH: 7.5 T: 2°CAssay Description:Compound affinity was measured using a fluorescence polarization anisotropy competition assay. Anisotropy measurements were carried out in 384-well, ...More data for this Ligand-Target Pair