BDBM289425 (R)-(4-(6-amino-5-(trifluoromethyl)pyridin-3-yl)-1-(bicyclo[1.1.1]pentan-1-yl)-1H-imidazol-2-yl)(cyclopropyl)methanol::US10093664, Example 5b

SMILES Nc1ncc(cc1C(F)(F)F)-c1cn(c(n1)[C@H](O)C1CC1)C12CC(C1)C2

InChI Key InChIKey=VFQSWWJADDGPOZ-LTITZTOOSA-N

Data  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 289425   

TargetMitogen-activated protein kinase kinase kinase 12(Homo sapiens (Human))
The University of Texas System

US Patent
LigandPNGBDBM289425((R)-(4-(6-amino-5-(trifluoromethyl)pyridin-3-yl)-1...)
Affinity DataKd:  2.30nMAssay Description:The DLK dissociation constants (Kd) have been determined in the KINOMEscan KdELECT Service at DiscoveRx. A fusion protein of full length of human DLK...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent