BDBM289510 5-(2-cyclopropyl-1-(3- (4-methylpiperazin-1- yl)bicyclo[1.1.1]- pentan-1-yl)-1H-imid- azol-4-yl)-3-(trifluoro- methyl)pyridin-2-amine::US10093664, Example 75

SMILES CN1CCN(CC1)C12CC(C1)(C2)n1cc(nc1C1CC1)-c1cnc(N)c(c1)C(F)(F)F

InChI Key InChIKey=JIICSEZAUZBVQG-UHFFFAOYSA-N

Data  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 289510   

TargetMitogen-activated protein kinase kinase kinase 12(Homo sapiens (Human))
The University of Texas System

US Patent
LigandPNGBDBM289510(5-(2-cyclopropyl-1-(3- (4-methylpiperazin-1- yl)bi...)
Affinity DataKd:  7.5nMAssay Description:The DLK dissociation constants (Kd) have been determined in the KINOMEscan KdELECT Service at DiscoveRx. A fusion protein of full length of human DLK...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent