BDBM29026 CHEMBL142996::cyanocyclopropylpropenamide, 11
SMILES O=C(Nc1ccc(cc1)-c1ccccc1)C(C#N)C(=O)C1CC1
InChI Key InChIKey=DIIHYLMEQKHUBY-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 29026
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
University of Leeds
University of Leeds
Affinity DataKi: 7nM IC50: 53nMAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum (isolate 3D7))
University of Leeds
University of Leeds
Affinity DataKi: 2.60E+4nM ΔG°: -6.25kcal/mole IC50: 2.24E+5nMpH: 8.0 T: 2°CAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Rattus norvegicus (rat))
Hoechst Marion Roussel
Curated by ChEMBL
Hoechst Marion Roussel
Curated by ChEMBL
Affinity DataIC50: 1.48E+3nMAssay Description:Inhibitory concentration tested against enzyme dihydroorotate dehydrogenase in ratMore data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Mus musculus)
Hoechst Marion Roussel
Curated by ChEMBL
Hoechst Marion Roussel
Curated by ChEMBL
Affinity DataIC50: 1.58E+3nMAssay Description:Inhibitory concentration tested on enzyme dihydroorotate dehydrogenase in mouseMore data for this Ligand-Target Pair