BDBM29075 PF-514273
SMILES CC(F)(F)CN1CCOc2c(nn(c2-c2ccc(Cl)cc2)-c2ccccc2Cl)C1=O
InChI Key InChIKey=FJMQJSUOOGOWBD-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 29075
Affinity DataKi: 0.820nMAssay Description:Antagonist activity at human CB1 receptor expressed in CHO-K1 cells assessed as inhibition of CP-55940-induced [35S]GTPgammaS binding incubated for 1...More data for this Ligand-Target Pair
Affinity DataKi: 1nM ΔG°: -12.5kcal/mole EC50: 0.820nMpH: 7.4 T: 2°CAssay Description:IC50 values for test compounds were determined from nonlinear regression analysis of data collected from ligand binding experiments. The inhibition c...More data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Displacement of [3H]SR141716A form human CB1 receptor expressed in HEK293 cells after 60 mins by beta countingMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:IC50 values for test compounds were determined from nonlinear regression analysis of data collected from ligand binding experiments. The inhibition c...More data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]CP-55940 from human CB2 receptor expressed in CHO-K1 cells after 60 mins by beta countingMore data for this Ligand-Target Pair