BDBM29266 isoquinoline N-oxide, 47

SMILES Cc1ncsc1C(=O)N(Cc1c[n+]([O-])cc2c(F)c(F)ccc12)c1cccc(Cl)c1

InChI Key InChIKey=IAZZGPMUNCIVOE-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 29266   

TargetNitric oxide synthase, brain(Homo sapiens (Human))
Kalypsys

LigandPNGBDBM29266(isoquinoline N-oxide, 47)
Affinity DataEC50:  3.20E+3nMT: 2°CAssay Description:HEK293 cells (ATCC) were transiently transfected with recombinant NOS and grown. Cells were trypsinized, resuspended to 5 00,000 cells/mL, and plated...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
Kalypsys

LigandPNGBDBM29266(isoquinoline N-oxide, 47)
Affinity DataEC50:  3.40E+4nMT: 2°CAssay Description:HEK293 cells (ATCC) were transiently transfected with recombinant NOS and grown. Cells were trypsinized, resuspended to 5 00,000 cells/mL, and plated...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Kalypsys

LigandPNGBDBM29266(isoquinoline N-oxide, 47)
Affinity DataEC50:  19nMT: 2°CAssay Description:HEK293 cells (ATCC) were transiently transfected with recombinant NOS and grown. Cells were trypsinized, resuspended to 5 00,000 cells/mL, and plated...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed