BDBM29270 quinolinone, 40

SMILES Cc1ncsc1C(=O)N(Cc1cc(=O)[nH]c2c(F)c(F)ccc12)c1cccc(Cl)c1

InChI Key InChIKey=GDVPRLPOKFPOSZ-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 29270   

TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Kalypsys

LigandPNGBDBM29270(quinolinone, 40)
Affinity DataEC50:  2nMT: 2°CAssay Description:HEK293 cells (ATCC) were transiently transfected with recombinant NOS and grown. Cells were trypsinized, resuspended to 5 00,000 cells/mL, and plated...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Kalypsys

LigandPNGBDBM29270(quinolinone, 40)
Affinity DataEC50:  120nMT: 2°CAssay Description:HEK293 cells (ATCC) were transiently transfected with recombinant NOS and grown. Cells were trypsinized, resuspended to 5 00,000 cells/mL, and plated...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
Kalypsys

LigandPNGBDBM29270(quinolinone, 40)
Affinity DataEC50:  3.00E+3nMT: 2°CAssay Description:HEK293 cells (ATCC) were transiently transfected with recombinant NOS and grown. Cells were trypsinized, resuspended to 5 00,000 cells/mL, and plated...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed