BDBM29313 dithioether 1,3,4-thiadiazole, 8f
SMILES [O-][N+](=O)c1cnc(Sc2nnc(Sc3ncc(s3)[N+]([O-])=O)s2)s1
InChI Key InChIKey=QYKQHNTWQJPQOZ-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 29313
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Burnham Institute For Medical Research
Burnham Institute For Medical Research
Affinity DataIC50: 800nMAssay Description:Compounds were tested for their ability to inhibit JNK1 phosphorylation of ATF2 in the Time-Resolved Fluorescence Resonance Energy Transfer (TR-FRET)...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Burnham Institute For Medical Research
Burnham Institute For Medical Research
Affinity DataIC50: 187nMAssay Description:Compound was evaluated for its ability to disrupt the interaction of pepJIP1 with JNK1 by using DELFIA assay. DELFIA is a heterogeneous assay whereby...More data for this Ligand-Target Pair