BDBM29314 dithioether 1,3,4-thiadiazole, 8g
SMILES OC(=O)c1cnc(Sc2nnc(Sc3ncc(s3)C(O)=O)s2)s1
InChI Key InChIKey=GWAGHGPQSBRPRG-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 29314
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Burnham Institute For Medical Research
Burnham Institute For Medical Research
Affinity DataIC50: 8.40E+4nMAssay Description:Compounds were tested for their ability to inhibit JNK1 phosphorylation of ATF2 in the Time-Resolved Fluorescence Resonance Energy Transfer (TR-FRET)...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Burnham Institute For Medical Research
Burnham Institute For Medical Research
Affinity DataIC50: 100nMAssay Description:Compound was evaluated for its ability to disrupt the interaction of pepJIP1 with JNK1 by using DELFIA assay. DELFIA is a heterogeneous assay whereby...More data for this Ligand-Target Pair