BDBM293918 3'-Fluoro-4-(5- fluoropyridin-3-yl)-N- hydroxy-2'-methyl- 1,2,3,6-tetrahydro-[1,1'- biphenyl]-1-carboxamide::US10106535, Example 44::US9617259, 44

SMILES Cc1c(F)cccc1C1(CCC(=CC1)c1cncc(F)c1)C(=O)NO

InChI Key InChIKey=ICXLDDDYWDJOGL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 293918   

TargetHistone deacetylase 4(Homo sapiens (Human))
Chdi Foundation

US Patent
LigandPNGBDBM293918(3'-Fluoro-4-(5- fluoropyridin-3-yl)-N- hydroxy-2'-...)
Affinity DataIC50:  490nMAssay Description:2 μl (200×) of each diluted solution and each control (full activity: 100% DMSO alone or full inhibition 1 mM) is stamped into V-bottomed polypr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 4(Homo sapiens (Human))
Chdi Foundation

US Patent
LigandPNGBDBM293918(3'-Fluoro-4-(5- fluoropyridin-3-yl)-N- hydroxy-2'-...)
Affinity DataIC50:  490nMAssay Description:5 μl of each solution of 1:20 diluted compound from above is transferred to a clear bottomed, black, 384-well assay plate using the Bravo or the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent