BDBM297710 2-({8-Fluoro-2-(1-fluoro- cyclopropyl)-4-[4-(3-methoxy- pyrazin-2-yl)-piperidin-1-yl]- quinazolin-6-yl}-methyl-amino)- ethanol::US10118902, Example 213::US10584103, Example 213

SMILES COc1nccnc1C1CCN(CC1)c1nc(nc2c(F)cc(cc12)N(C)CCO)C1(F)CC1

InChI Key InChIKey=SSLJPKXWVAGMPD-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 297710   

TargetNeurotensin receptor type 1(Homo sapiens (Human))
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandPNGBDBM297710(2-({8-Fluoro-2-(1-fluoro- cyclopropyl)-4-[4-(3-met...)
Affinity DataEC50:  1.25E+3nMAssay Description:NTSR1 (NTR1) CHO cells are plated in 20 μL of assay media containing Ham's F12 supplemented with 10% fetal bovine serum and 0.4 mg/mL G418 a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNeurotensin receptor type 1(Homo sapiens (Human))
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandPNGBDBM297710(2-({8-Fluoro-2-(1-fluoro- cyclopropyl)-4-[4-(3-met...)
Affinity DataEC50:  1.25E+3nMAssay Description:NTSR1 (NTR1) CHO cells are plated in 20 uL of assay media containing Ham's F12 supplemented with 10% fetal bovine serum and 0.4 mg/mL G418 at a c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent