BDBM298474 US10125101, Example 24

SMILES OC(=O)[C@H]1C[C@@H]1c1ccc(N[C@@H]2CCc3c2c(F)ccc3-c2c(Cl)cccc2Cl)cn1

InChI Key InChIKey=FZAKFHNOSCCQOG-CKJXQJPGSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 298474   

TargetFree fatty acid receptor 1(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM298474(US10125101, Example 24)
Affinity DataEC50:  4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCytochrome P450 2C9(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM298474(US10125101, Example 24)
Affinity DataIC50:  2.20E+4nMAssay Description:The inhibition of cytochrome P450 2C9-isoenzyme catalyzed hydroxylation of diclofenac by the test compound is assayed at 37° C. with human liver micr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCytochrome P450 2C8(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM298474(US10125101, Example 24)
Affinity DataIC50:  1.10E+4nMAssay Description:The inhibition of cytochrome P450 2C8-isoenzyme catalyzed deethylation of amodiaquine by the test compound is assayed at 37° C. with human liver micr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent