BDBM29889 alkynyl ether, 31

SMILES CCC#CCOc1cc(COc2ccc(Cl)cc2)ccc1Sc1ccc(OCC(O)=O)c2CCCCc12

InChI Key InChIKey=JPEYVXVKOZZIGX-UHFFFAOYSA-N

Data  3 KI  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 29889   

TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Amgen

LigandPNGBDBM29889(alkynyl ether, 31)
Affinity DataKi:  36nM EC50:  350nMAssay Description:The human PPARdelta ligand binding was directly measured using a scintillation proximity assay. Plates were read on a Packard TopCount. IC50 values f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Amgen

LigandPNGBDBM29889(alkynyl ether, 31)
Affinity DataKi:  39nM EC50:  560nMAssay Description:The human PPARgamma ligand binding was directly measured using a filtration assay in a UniFilter 350 96-well assay plate (Polyfiltronics). The reacti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Amgen

LigandPNGBDBM29889(alkynyl ether, 31)
Affinity DataKi:  2.00E+3nM ΔG°:  -7.69kcal/mole EC50: >1.00E+5nMpH: 7.1 T: 2°CAssay Description:The human PPARalpha ligand binding was directly measured using a scintillation proximity assay. Plates were read on a Packard TopCount. IC50 values f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed