BDBM299135 (6S,8R)-7-(2- fluoro-2- methylpropyl)-6- (2-methoxy-4- (2-(3- methoxyazetidin- 1-yl)ethoxy) phenyl)-8-methyl- 6,7,8,9- tetrahydro-3H- pyrazolo[4,3- f]isoquinoline::US10125135, Example 24

SMILES COC1CN(CCOc2ccc([C@H]3N(CC(C)(C)F)[C@H](C)Cc4c3ccc3[nH]ncc43)c(OC)c2)C1

InChI Key

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 299135   

TargetEstrogen receptor(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM299135((6S,8R)-7-(2- fluoro-2- methylpropyl)-6- (2-methox...)
Affinity DataIC50:  3.70nMAssay Description:The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha LBD (GST)) was assessed in competition assays us...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent