BDBM299137 2,2-difluoro-3- ((6S,8R)-6-(2- fluoro-4-(2-(3- (fluoromethyl) azetidin-1- yl)ethoxy)-6- methoxyphenyl)- 8-methyl-8,9- dihydro-3H- pyrazolo[4,3- f]isoquinolin- 7(6H)-yl)propan- 1-ol::US10125135, Example 26

SMILES COc1cc(OCCN2CC(CF)C2)cc(F)c1[C@H]1N(CC(F)(F)CO)[C@H](C)Cc2c1ccc1[nH]ncc21

InChI Key

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 299137   

TargetEstrogen receptor(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM299137(2,2-difluoro-3- ((6S,8R)-6-(2- fluoro-4-(2-(3- (fl...)
Affinity DataIC50:  3.80nMAssay Description:The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha LBD (GST)) was assessed in competition assays us...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent