BDBM299145 (6S,8R)-6-(2,6- difluoro-4-(2-(3- (fluoromethyl) azetidin-1- yl)ethoxy) phenyl)-7-(2,3- difluoropropyl)- 8-methyl- 6,7,8,9- tetrahydro-3H- pyrazolo[4,3- f]isoquinoline::US10125135, Example 34::US10125135, Example 35
SMILES C[C@@H]1Cc2c(ccc3[nH]ncc23)[C@H](N1CC(F)CF)c1c(F)cc(OCCN2CC(CF)C2)cc1F
InChI Key
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 299145
Affinity DataIC50: 2.70nMAssay Description:The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha LBD (GST)) was assessed in competition assays us...More data for this Ligand-Target Pair
Affinity DataIC50: 3.80nMAssay Description:The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha LBD (GST)) was assessed in competition assays us...More data for this Ligand-Target Pair