BDBM299504 6-[3-[6-(dimethyl- amino)-2-pyridyl]- 1-piperidyl] pyrido[3,2-d] pyrimidin- 4-amine::US9592235, Example 277::US9855269, Compound 124

SMILES CN(C)c1cccc(n1)C1CCCN(C1)c1ccc2ncnc(N)c2n1

InChI Key InChIKey=SQZDWLWLHXRZJE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 299504   

TargetMitogen-activated protein kinase kinase kinase kinase 4(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM299504(6-[3-[6-(dimethyl- amino)-2-pyridyl]- 1-piperidyl]...)
Affinity DataIC50:  290nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase kinase 4(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM299504(6-[3-[6-(dimethyl- amino)-2-pyridyl]- 1-piperidyl]...)
Affinity DataIC50:  290nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent