BDBM299633 (2S,4S)-5-(3′-Chlorobiphenyl-4-yl)-2-ethoxymethyl-4-[(3-hydroxyisoxazole-5-carbonyl)amino]pentanoic Acid::US9593110, Example 8

SMILES CCOC[C@H](C[C@@H](Cc1ccc(cc1)-c1cccc(Cl)c1)NC(=O)c1cc(O)no1)C(=O)OCC

InChI Key InChIKey=UQKXXHFWGRPQHA-RBBKRZOGSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 299633   

TargetNeprilysin(Homo sapiens (Human))
Theravence Biopharma R&D Ip

US Patent
LigandPNGBDBM299633((2S,4S)-5-(3′-Chlorobiphenyl-4-yl)-2-ethoxym...)
Affinity DataKi: <1nMAssay Description:Recombinant human NEP and recombinant human ACE were obtained commercially (R&D Systems, Minneapolis, Minn., catalog numbers 1182-ZN and 929-ZN, resp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent