BDBM300238 US9593127, Example 12::[3-[2-(m-tolyl)ethynyl]- 3a,4,5,6a- tetrahydropyrrolo[3,2- d]isoxazol-6-yl]-(1- piperidyl)methanone

SMILES Cc1cccc(c1)C#CC1=NOC2C1CCN2C(=O)N1CCCCC1

InChI Key InChIKey=CZDHIOSRCRPHPR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 300238   

TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Recordati Ireland

US Patent
LigandPNGBDBM300238(US9593127, Example 12 | [3-[2-(m-tolyl)ethynyl]- 3...)
Affinity DataIC50:  10.6nMAssay Description:Affinity at transmembrane glutamate metabotropic mGluR5 receptor subtypes was evaluated according to the methods of Anderson (Anderson et al., J Phar...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent