BDBM301283 3-(2,6-difluoro-3,5-dimethoxyphenyl)-1,3,4,7-tetrahydro-2H-pyrazolo[4'',3'':5,6]pyrido[4,3-d]pyrimidin-2-one::BDBM301287::US10131667, Example 99::US11053246, Example 99::US9611267, Example 99

SMILES COc1cc(OC)c(F)c(N2Cc3cnc4[nH]ncc4c3NC2=O)c1F

InChI Key InChIKey=NUAOTQQBUWYKAJ-UHFFFAOYSA-N

Data  12 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 301283   

TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM301283(3-(2,6-difluoro-3,5-dimethoxyphenyl)-1,3,4,7-tetra...)
Affinity DataIC50: <100nMAssay Description:The inhibitor potency of the exemplified compounds was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM301283(3-(2,6-difluoro-3,5-dimethoxyphenyl)-1,3,4,7-tetra...)
Affinity DataIC50: <100nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM301283(3-(2,6-difluoro-3,5-dimethoxyphenyl)-1,3,4,7-tetra...)
Affinity DataIC50: <100nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM301283(3-(2,6-difluoro-3,5-dimethoxyphenyl)-1,3,4,7-tetra...)
Affinity DataIC50: <100nMAssay Description:The inhibitor potency of the exemplified compounds was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM301283(3-(2,6-difluoro-3,5-dimethoxyphenyl)-1,3,4,7-tetra...)
Affinity DataIC50: <100nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM301283(3-(2,6-difluoro-3,5-dimethoxyphenyl)-1,3,4,7-tetra...)
Affinity DataIC50: <100nMAssay Description:The inhibitor potency of the exemplified compounds was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM301283(3-(2,6-difluoro-3,5-dimethoxyphenyl)-1,3,4,7-tetra...)
Affinity DataIC50: <100nMAssay Description:The inhibitor potency of the exemplified compounds was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM301283(3-(2,6-difluoro-3,5-dimethoxyphenyl)-1,3,4,7-tetra...)
Affinity DataIC50: <100nMAssay Description:The inhibitor potency of the exemplified compounds was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM301283(3-(2,6-difluoro-3,5-dimethoxyphenyl)-1,3,4,7-tetra...)
Affinity DataIC50: <100nMAssay Description:The inhibitor potency of the exemplified compounds was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM301283(3-(2,6-difluoro-3,5-dimethoxyphenyl)-1,3,4,7-tetra...)
Affinity DataIC50: <100nMAssay Description:The inhibitor potency of the exemplified compounds was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM301283(3-(2,6-difluoro-3,5-dimethoxyphenyl)-1,3,4,7-tetra...)
Affinity DataIC50: <100nMAssay Description:The inhibitor potency of the exemplified compounds was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM301283(3-(2,6-difluoro-3,5-dimethoxyphenyl)-1,3,4,7-tetra...)
Affinity DataIC50: <100nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent