BDBM302861 (5′S)-5-Methyl-4′,5′-dihydrospiro[piperidine-4,7′-thieno[2,3-c]pyran]::BDBM302862::US9598431, 4

SMILES CCS(=O)(=O)c1ccc(CNC(=O)c2cc3C[C@@H](C)OC4(CCN(CC4)C(C)c4cnc(nc4)C(F)(F)F)c3s2)nc1

InChI Key InChIKey=ILXLMNLDODDHOQ-QNSVNVJESA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 302861   

TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Eli Lilly

US Patent
LigandPNGBDBM302861((5′S)-5-Methyl-4′,5′-dihydrospir...)
Affinity DataKi:  148nMAssay Description:Receptor competition binding assays are run in a buffer made up of DPBS (1 L) (Hyclone #SH30028.03), 2.2 g BSA Fraction v (Roche #9048-46-8), 100 mL ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Eli Lilly

US Patent
LigandPNGBDBM302861((5′S)-5-Methyl-4′,5′-dihydrospir...)
Affinity DataKi:  153nMAssay Description:Receptor competition binding assays are run in a buffer made up of DPBS (1 L) (Hyclone #SH30028.03), 2.2 g BSA Fraction v (Roche #9048-46-8), 100 mL ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNuclear receptor ROR-beta(Homo sapiens (Human))
Eli Lilly

US Patent
LigandPNGBDBM302861((5′S)-5-Methyl-4′,5′-dihydrospir...)
Affinity DataKi:  407nMAssay Description:Receptor competition binding assays are run in a buffer made up of DPBS (1 L) (Hyclone #SH30028.03), 2.2 g BSA Fraction v (Roche #9048-46-8), 100 mL ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNuclear receptor ROR-beta(Homo sapiens (Human))
Eli Lilly

US Patent
LigandPNGBDBM302861((5′S)-5-Methyl-4′,5′-dihydrospir...)
Affinity DataKi:  2.19E+3nMAssay Description:Receptor competition binding assays are run in a buffer made up of DPBS (1 L) (Hyclone #SH30028.03), 2.2 g BSA Fraction v (Roche #9048-46-8), 100 mL ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNuclear receptor ROR-alpha(Homo sapiens (Human))
Eli Lilly

US Patent
LigandPNGBDBM302861((5′S)-5-Methyl-4′,5′-dihydrospir...)
Affinity DataKi: >2.04E+4nMAssay Description:Receptor competition binding assays are run in a buffer made up of DPBS (1 L) (Hyclone #SH30028.03), 2.2 g BSA Fraction v (Roche #9048-46-8), 100 mL ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNuclear receptor ROR-alpha(Homo sapiens (Human))
Eli Lilly

US Patent
LigandPNGBDBM302861((5′S)-5-Methyl-4′,5′-dihydrospir...)
Affinity DataKi: >2.04E+4nMAssay Description:Receptor competition binding assays are run in a buffer made up of DPBS (1 L) (Hyclone #SH30028.03), 2.2 g BSA Fraction v (Roche #9048-46-8), 100 mL ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent