BDBM30329 Naphthoic acid-based analog, 1b

SMILES CC(C)c1onc(c1COc1ccc(cc1)-c1ccc2c(cccc2c1)C(O)=O)-c1c(Cl)cccc1Cl

InChI Key InChIKey=TUOXXRMLFZBSTB-UHFFFAOYSA-N

Data  6 EC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 30329   

TargetBile acid receptor(Homo sapiens (Human))
Gsk

LigandPNGBDBM30329(Naphthoic acid-based analog, 1b)
Affinity DataEC50:  87nMpH: 7.5 T: 2°CAssay Description:The assay measures ligand-mediated interaction of the SRC-1 peptide with the FXR ligand binding domain, using biotinylated FXR LBD coupled to allophy...More data for this Ligand-Target Pair
TargetBile acid receptor(Homo sapiens (Human))
Gsk

LigandPNGBDBM30329(Naphthoic acid-based analog, 1b)
Affinity DataEC50:  68nMAssay Description:The cell-based assay measures the ligand-mediated luminescense resulting from FXR-induced transcription of a luciferase reporter. FXR and the lucifer...More data for this Ligand-Target Pair