BDBM304390 US10144715, Compound 9-5::methyl 2-(2-(tert-butyl)-4-(4-fluoro-3-(methylsulfonyl)phenyl)piperazin-1-yl)-4-(trifluoromethyl)pyrimidine-5-carboxylate

SMILES COC(=O)c1cnc(nc1C(F)(F)F)N1CCN(CC1C(C)(C)C)c1ccc(F)c(c1)S(C)(=O)=O

InChI Key InChIKey=CRRQUBDXEDTMJH-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 304390   

TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Vitae Pharmaceuticals

US Patent
LigandPNGBDBM304390(US10144715, Compound 9-5 | methyl 2-(2-(tert-butyl...)
Affinity DataKi:  9nMAssay Description:Compounds of the invention were assessed in a competition binding assay where different concentrations of compounds were incubated with the LXR ligan...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
Vitae Pharmaceuticals

US Patent
LigandPNGBDBM304390(US10144715, Compound 9-5 | methyl 2-(2-(tert-butyl...)
Affinity DataKi:  41nMAssay Description:Compounds of the invention were assessed in a competition binding assay where different concentrations of compounds were incubated with the LXR ligan...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent