BDBM304673 (S)-1-(((3S,6r)-1,1-difluorospiro[2.5]octan-6-yl)methyl)-4-(3-(methylsulfonyl)phenyl)-2-phenylpiperazine::US10144715, Compound 48-71

SMILES CS(=O)(=O)c1cccc(c1)N1CCN(C[C@H]2CC[C@@]3(CC3(F)F)CC2)[C@H](C1)c1ccccc1

InChI Key InChIKey=KQGULCLQMZRZGO-NIJXNBFTSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 304673   

TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Vitae Pharmaceuticals

US Patent
LigandPNGBDBM304673((S)-1-(((3S,6r)-1,1-difluorospiro[2.5]octan-6-yl)m...)
Affinity DataKi:  10nMAssay Description:Compounds of the invention were assessed in a competition binding assay where different concentrations of compounds were incubated with the LXR ligan...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
Vitae Pharmaceuticals

US Patent
LigandPNGBDBM304673((S)-1-(((3S,6r)-1,1-difluorospiro[2.5]octan-6-yl)m...)
Affinity DataKi:  50nMAssay Description:Compounds of the invention were assessed in a competition binding assay where different concentrations of compounds were incubated with the LXR ligan...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent