BDBM307577 (2-(2H-1,2,3-triazol-2-yl)phenyl)((2R,4R)-4- (isoquinolin-1-ylamino)-2-methylpyrrolidin- 1-yl)methanone::US10150751, Example 12
SMILES C[C@@H]1C[C@H](CN1C(=O)c1ccccc1-n1nccn1)Nc1nccc2ccccc12
InChI Key InChIKey=LDRXLAMNOJZDSW-SJLPKXTDSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 307577
Affinity DataIC50: 257nMAssay Description: All reagents were from GIBCO-Invitrogen Corp. The seeded plates are incubated overnight at 37° C. and 5% CO2. Ala-6,12 human orexin-A as the agonist...More data for this Ligand-Target Pair
Affinity DataIC50: 15.3nMAssay Description: All reagents were from GIBCO-Invitrogen Corp. The seeded plates are incubated overnight at 37° C. and 5% CO2. Ala-6,12 human orexin-A as the agonist...More data for this Ligand-Target Pair