BDBM310005 2-(5-((Cyclopropylmethyl)(4-(trifluoromethyl)naphthalen-1-yl)amino)-3-methoxypicolinoyl)cyclopropanecarboxylic acid::US9657001, 34

SMILES CCOC(=O)C1CC1C(=O)c1ncc(cc1OC)N(CC1CC1)c1ccc(c2ccccc12)C(F)(F)F

InChI Key InChIKey=HWKLRWBWPXPRJY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 310005   

TargetLeukotriene C4 synthase(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM310005(2-(5-((Cyclopropylmethyl)(4-(trifluoromethyl)napht...)
Affinity DataIC50:  19nMAssay Description:In the assay, LTC4 synthase catalyses the reaction where the substrate LTA4 methyl ester is converted to LTC4 methyl ester.In order to obtain IC50-va...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent