BDBM310237 (2S,3R)-3-(5-cyano-2-pyrimidinyl)-N-(4-(2,6-dimethoxyphenyl)-5-((2S)-tetrahydro-2-furanyl)-4H-1,2,4-triazol-3-yl)-2-butanesulfonamide or (2S,3R)-3-(5-cyano-2-pyrimidinyl)-N-(4-(2,6-dimethoxyphenyl)-5-((2R)-tetrahydro-2-furanyl)-4H-1,2,4-triazol-3-yl)-2-butanesulfonamide::US10150760, Example 24.0

SMILES COc1cccc(OC)c1-n1c(NS(=O)(=O)[C@@H](C)[C@H](C)c2ncc(Cl)cn2)nnc1[C@@H]1CCCO1

InChI Key InChIKey=QPZRZYJXSTYOHW-DEYYWGMASA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 310237   

TargetApelin receptor(Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM310237((2S,3R)-3-(5-cyano-2-pyrimidinyl)-N-(4-(2,6-dimeth...)
Affinity DataEC50:  4.5nMAssay Description:The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV-3 expression vector (Sig...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent