BDBM310240 (2S,3R)-3-(5-chloro-2-pyrimidinyl)-N-(4-(4,6-dimethoxy-5-pyrimidinyl)-5-(3-oxetanyl)-4H-1,2,4-triazol-3-yl)-2-butanesulfonamide::US10150760, Example 35.0

SMILES COc1ncnc(OC)c1-n1c(NS(=O)(=O)[C@@H](C)[C@H](C)c2ncc(Cl)cn2)nnc1C1COC1

InChI Key InChIKey=JRSSWEAHIWVNDI-QWRGUYRKSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 310240   

TargetApelin receptor(Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM310240((2S,3R)-3-(5-chloro-2-pyrimidinyl)-N-(4-(4,6-dimet...)
Affinity DataEC50:  730nMAssay Description:The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV-3 expression vector (Sig...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent