BDBM31124 5-hydroxy-1H-benzo[g]indole-3-carboxylate, 11c

SMILES CCOC(=O)c1c(Cc2ccc(Cl)cc2)[nH]c2c1cc(O)c1ccccc21

InChI Key InChIKey=PQKLMAZXCPRECG-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 31124   

TargetProstaglandin E synthase(Homo sapiens (Human))
Eberhard Karls University Tuebingen

Curated by ChEMBL
LigandPNGBDBM31124(5-hydroxy-1H-benzo[g]indole-3-carboxylate, 11c)
Affinity DataIC50:  3.40E+3nMAssay Description:Inhibition of mPGES1 in IL1beta induced human A549 cell microsomal membrane assessed as blockade of conversion of PGH2 to PGE2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Friedrich Alexander University Erlangen

LigandPNGBDBM31124(5-hydroxy-1H-benzo[g]indole-3-carboxylate, 11c)
Affinity DataIC50:  84nM EC50:  1.20E+3nMpH: 7.4 T: 2°CAssay Description:For determination of the activity of 5-LO in 40000g supernatant (S40), aliquots of the supernatants were added to reaction mix, and were preincubated...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed