BDBM311517 5-{[(1R,2R)-2-amino- 3,3- difluorocyclohexyl]amino}- N-(3-carbamoyl-1- methyl-1H-pyrazol-4- yl)pyrazolo[1,5- a]pyrimidine-3- carboxamide trifluoroacetate::US10155765, Example 3
SMILES Cn1cc(NC(=O)c2cnn3ccc(N[C@@H]4CCCC(F)(F)[C@@H]4N)nc23)c(n1)C(N)=O
InChI Key InChIKey=FEZFMDKBZLALJK-QMTHXVAHSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 311517
Affinity DataIC50: 32nMAssay Description:The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp...More data for this Ligand-Target Pair