BDBM31160 3-hydroxyquinolin-2(1H)-one, 14

SMILES Cc1cccc2[nH]c(=O)c(O)cc12

InChI Key InChIKey=NRNHMRFPCJTZAW-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 31160   

TargetD-amino-acid oxidase(Homo sapiens (Human))
Pfizer

LigandPNGBDBM31160(3-hydroxyquinolin-2(1H)-one, 14)
Affinity DataIC50:  16nMpH: 8.5 T: 2°CAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD-amino-acid oxidase(Rattus norvegicus (rat))
Pfizer

LigandPNGBDBM31160(3-hydroxyquinolin-2(1H)-one, 14)
Affinity DataIC50:  8.47E+3nMAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD-aspartate oxidase(Homo sapiens (Human))
Pfizer

LigandPNGBDBM31160(3-hydroxyquinolin-2(1H)-one, 14)
Affinity DataIC50:  5.46E+4nMAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-aspartic acid was linke...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed