BDBM31169 3-hydroxyquinolin-2(1H)-one, 23::US9701638, 14

SMILES Cc1c(O)c(=O)[nH]c2ccccc12

InChI Key InChIKey=XSRVOYKJNNIOQK-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 31169   

TargetD-amino-acid oxidase(Homo sapiens (Human))
Pfizer

LigandPNGBDBM31169(3-hydroxyquinolin-2(1H)-one, 23 | US9701638, 14)
Affinity DataIC50:  1.73E+4nMpH: 8.5 T: 2°CAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHemagglutinin(Influenza A virus (strain swl A/California/04/2009...)
Rutgers, The State University of New Jersey

US Patent
LigandPNGBDBM31169(3-hydroxyquinolin-2(1H)-one, 23 | US9701638, 14)
Affinity DataIC50: >1.00E+5nMpH: 7.5Assay Description:The PAN domain has been shown to cleave ssRNA as well as ssDNA. To demonstrate the inhibition of endonuclease cleavage by PAN, a high throughput assa...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetD-aspartate oxidase(Homo sapiens (Human))
Pfizer

LigandPNGBDBM31169(3-hydroxyquinolin-2(1H)-one, 23 | US9701638, 14)
Affinity DataIC50:  3.23E+4nMAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-aspartic acid was linke...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed