BDBM311767 6-(7-(4-Fluorophenyl)-2-(trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyridin-8-yl)benzo[d]thiazol-2(3H)-one::US10155769, Example 5
SMILES Fc1ccc(cc1)-c1ccn2nc(nc2c1-c1ccc2[nH]c(=O)sc2c1)C(F)(F)F
InChI Key InChIKey=MHLASTDYGRVTDH-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 311767
TargetVoltage-dependent calcium channel gamma-2 subunit(Homo sapiens (Human))
Janssen Pharmaceutica
US Patent
Janssen Pharmaceutica
US Patent
Affinity DataIC50: 0.251nMAssay Description:An in vitro assay was used to determine the potency of test compounds as inhibitors of the glutamate response of the channel formed by GluA1o-γ8...More data for this Ligand-Target Pair