BDBM311767 6-(7-(4-Fluorophenyl)-2-(trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyridin-8-yl)benzo[d]thiazol-2(3H)-one::US10155769, Example 5

SMILES Fc1ccc(cc1)-c1ccn2nc(nc2c1-c1ccc2[nH]c(=O)sc2c1)C(F)(F)F

InChI Key InChIKey=MHLASTDYGRVTDH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 311767   

TargetVoltage-dependent calcium channel gamma-2 subunit(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM311767(6-(7-(4-Fluorophenyl)-2-(trifluoromethyl)-[1,2,4]t...)
Affinity DataIC50:  0.251nMAssay Description:An in vitro assay was used to determine the potency of test compounds as inhibitors of the glutamate response of the channel formed by GluA1o-γ8...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent