BDBM311842 8-(7-Chloro-1H-indazol-5-yl)-7-cyclopropyl-2-(difluoromethyl)-5-methyl-imidazo[1,2-c]pyrimidine::US10155769, Example 80
SMILES Cc1nc(C2CC2)c(-c2cc(Cl)c3[nH]ncc3c2)c2nc(cn12)C(F)F
InChI Key InChIKey=JSBWRTNBGLRLCE-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 311842
TargetVoltage-dependent calcium channel gamma-2 subunit(Homo sapiens (Human))
Janssen Pharmaceutica
US Patent
Janssen Pharmaceutica
US Patent
Affinity DataIC50: 0.631nMAssay Description:An in vitro assay was used to determine the potency of test compounds as inhibitors of the glutamate response of the channel formed by GluA1o-γ8...More data for this Ligand-Target Pair