BDBM31283 Chalcone derivative, N

SMILES OC(=O)COc1c(Br)cc(\C=C\C(=O)c2ccc3ccccc3c2)cc1Br

InChI Key InChIKey=MBAPQUAKCNYSCD-VMPITWQZSA-N

Data  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 31283   

TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Max Planck Institute

LigandPNGBDBM31283(Chalcone derivative, N)
Affinity DataKd:  2.70E+5nMpH: 7.4 T: 2°CAssay Description:NMR measurements consisted of monitoring changes in chemical shifts and line widths of the backbone amide resonances of uniformly 15N-enriched MDM2 s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed