BDBM312870 1-[3-[2-[(3R)-3-hydroxy-1- methyl-2-oxo-pyrrolidin-3- yl]ethynyl]phenyl]-6-methoxy- pyrazolo[3,4-d]pyrimidine- 3-carboxamide::US9605005, Example 160

SMILES COc1ncc2c(nn(-c3cccc(c3)C#C[C@]3(O)CCN(C)C3=O)c2n1)C(N)=O

InChI Key InChIKey=TWRHVSCDYGADNH-FQEVSTJZSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 312870   

TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM312870(1-[3-[2-[(3R)-3-hydroxy-1- methyl-2-oxo-pyrrolidin...)
Affinity DataKi:  0.130nMAssay Description:The ability of the nuclear factor-kappa B (NF-kB)-inducing kinase (NIK) to catalyze the hydrolysis of adenosine-5′-triphosphate (ATP) was monit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent