BDBM312896 6-chloro-1-[2-fluoro-5-[2-[(3R)- 3-hydroxy-1-methyl-2- oxo-pyrrolidin-3-yl]ethynyl] phenyl]imidazo[1,5-a]pyri- dine-3-carboxamide::US9605005, Example 186
SMILES CN1CC[C@@](O)(C#Cc2ccc(F)c(c2)-c2nc(C(N)=O)n3cc(Cl)ccc23)C1=O
InChI Key InChIKey=VLWVKASAOWNBTH-NRFANRHFSA-N
Data 1 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 312896
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
Genentech
US Patent
Genentech
US Patent
Affinity DataKi: 0.100nMAssay Description:The ability of the nuclear factor-kappa B (NF-kB)-inducing kinase (NIK) to catalyze the hydrolysis of adenosine-5′-triphosphate (ATP) was monit...More data for this Ligand-Target Pair