BDBM314076 US10167313, Compound 70::Z-Asp-(D,L Ala(2'-quinolyl))-Val- Aspphenyl vinylsulfone

SMILES CC(C)[C@H](NC(=O)[C@@H](Cc1ccc2ccccc2n1)NC(=O)[C@H](CC(O)=O)NC(=O)OCc1ccccc1)C(=O)N[C@@H](CC(O)=O)\C=C\S(=O)(=O)c1ccccc1

InChI Key InChIKey=CPFXCSLAAJOPLW-IHJNOYNJSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 314076   

TargetCaspase-3(Homo sapiens (Human))
Genesis Technologies

US Patent
LigandPNGBDBM314076(US10167313, Compound 70 | Z-Asp-(D,L Ala(2'-quinol...)
Affinity DataIC50:  300nMAssay Description:Selectivity of compound 55, compound 63, compound 48, compound 57, compound 88 toward caspase-1 (pro-inflammatory group), caspase-5 (group I), caspas...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCaspase-9(Homo sapiens (Human))
Genesis Technologies

US Patent
LigandPNGBDBM314076(US10167313, Compound 70 | Z-Asp-(D,L Ala(2'-quinol...)
Affinity DataIC50: >1.00E+4nMAssay Description:Selectivity of compound 55, compound 63, compound 48, compound 57, compound 88 toward caspase-1 (pro-inflammatory group), caspase-5 (group I), caspas...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCaspase-7(Homo sapiens (Human))
Genesis Technologies

US Patent
LigandPNGBDBM314076(US10167313, Compound 70 | Z-Asp-(D,L Ala(2'-quinol...)
Affinity DataIC50: >1.00E+4nMAssay Description:Selectivity of compound 55, compound 63, compound 48, compound 57, compound 88 toward caspase-1 (pro-inflammatory group), caspase-5 (group I), caspas...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCaspase-5(Homo sapiens (Human))
Genesis Technologies

US Patent
LigandPNGBDBM314076(US10167313, Compound 70 | Z-Asp-(D,L Ala(2'-quinol...)
Affinity DataIC50: >1.00E+4nMAssay Description:Selectivity of compound 55, compound 63, compound 48, compound 57, compound 88 toward caspase-1 (pro-inflammatory group), caspase-5 (group I), caspas...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent