BDBM317217 US9617272, Compound 101::US9981973, Compound 101

SMILES C1c2cn[nH]c2-c2ccccc12

InChI Key InChIKey=DGYDIEIMGSEYDK-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 317217   

TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Newlink Genetics

US Patent
LigandPNGBDBM317217(US9617272, Compound 101 | US9981973, Compound 101)
Affinity DataIC50: >1.00E+4nMAssay Description:The IC50 values for each compound were determined by testing the activity of IDO in a mixture containing 50 mM potassium phosphate buffer at pH 6.5; ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTryptophan 2,3-dioxygenase(Homo sapiens (Human))
Newlink Genetics

US Patent
LigandPNGBDBM317217(US9617272, Compound 101 | US9981973, Compound 101)
Affinity DataIC50:  1.00E+3nMAssay Description:The IC50 values for each compound were determined by testing the activity of TDO in a mixture containing 50 mM potassium phosphate buffer at pH 6.5; ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Newlink Genetics

US Patent
LigandPNGBDBM317217(US9617272, Compound 101 | US9981973, Compound 101)
Affinity DataIC50: >1.00E+4nMAssay Description:The IC50 values for each compound were determined by testing the activity of IDO in a mixture containing 50 mM potassium phosphate buffer at pH 6.5; ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTryptophan 2,3-dioxygenase(Homo sapiens (Human))
Newlink Genetics

US Patent
LigandPNGBDBM317217(US9617272, Compound 101 | US9981973, Compound 101)
Affinity DataIC50:  550nMAssay Description:The IC50 values for each compound were determined by testing the activity of TDO in a mixture containing 50 mM potassium phosphate buffer at pH 6.5; ...More data for this Ligand-Target Pair
In DepthDetails US Patent