BDBM317679 US11337976, Compound P-0050::US20230277534, Compound P-0050::US9624213, Compound P-0050

SMILES Fc1c(NS(=O)(=O)N2CCCC2)cccc1C(=O)c1c[nH]c2ncc(cc12)-c1ccc(cc1)C1(CC1)C#N

InChI Key InChIKey=HOQZFUZEAFCTRT-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 317679   

TargetSerine/threonine-protein kinase B-raf [V600E](Homo sapiens (Human))
Plexxikon

US Patent
LigandPNGBDBM317679(US11337976, Compound P-0050 | US20230277534, Compo...)
Affinity DataIC50: <100nMAssay Description:Assays for biochemical and cell based activity are known in the art, for example, as described in PCT publication WO 2007/002433, the disclosure of w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase B-raf [V600E](Homo sapiens (Human))
Plexxikon

US Patent
LigandPNGBDBM317679(US11337976, Compound P-0050 | US20230277534, Compo...)
Affinity DataIC50: <100nMAssay Description:The biochemical activity IC50 values are determined with respect to inhibition of B-Raf V600E kinase activity or p-Erk kinase activity, where inhibit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase B-raf [V600E](Homo sapiens (Human))
Plexxikon

US Patent
LigandPNGBDBM317679(US11337976, Compound P-0050 | US20230277534, Compo...)
Affinity DataIC50: <100nMAssay Description:For example, the biochemical activity IC50 values are determined with respect to inhibition of B-Raf V600E kinase activity or p-Erk kinase activity, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent