BDBM31830 quinazoline-pyrazolourea hybrid compound, 3d

SMILES Cc1cccc(c1)-n1nc(cc1NC(=O)Nc1cccc(Nc2ncnc3ccc(cc23)[N+]([O-])=O)c1)C(C)(C)C

InChI Key InChIKey=KYFLIYLKGJJPKB-UHFFFAOYSA-N

Data  1 IC50  1 Kd  1 Other

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 31830   

TargetProto-oncogene tyrosine-protein kinase Src [251-533,T338M](Gallus gallus (Chicken))
Chemical Genomics Centre of The Max Planck Society

LigandPNGBDBM31830(quinazoline-pyrazolourea hybrid compound, 3d)
Affinity DatapH: 7.0 T: 2°CAssay Description:IC50 determinations for cSrc kinases were measured with the HTRF KinEASE-TK assay from Cisbio according to the manufacturer instructions. A biotinyla...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Gallus gallus (Chicken))
Chemical Genomics Centre of The Max Planck Society

LigandPNGBDBM31830(quinazoline-pyrazolourea hybrid compound, 3d)
Affinity DataIC50:  207nM Kd:  256nMpH: 7.0 T: 2°CAssay Description:IC50 determinations for cSrc kinases were measured with the HTRF KinEASE-TK assay from Cisbio according to the manufacturer instructions. A biotinyla...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed