BDBM31833 2,4-Bisanilinopyrimidine, 5

SMILES Oc1ccc(Nc2ncc(F)c(Nc3ccc(NC(=O)c4ccccc4Cl)cc3)n2)cc1

InChI Key InChIKey=ZYURNHOEBWWJHI-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 31833   

TargetAurora kinase B(Homo sapiens (Human))
Genentech

LigandPNGBDBM31833(2,4-Bisanilinopyrimidine, 5)
Affinity DataIC50:  1.40E+3nMpH: 7.5 T: 2°CAssay Description:Aurora kinase was assayed in ELISA format using a GST fusion of the N-terminus of Histone H3 as substrate. Plates were coated with substrate, and the...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
Genentech

LigandPNGBDBM31833(2,4-Bisanilinopyrimidine, 5)
Affinity DataIC50:  6nMpH: 7.5 T: 2°CAssay Description:Aurora kinase was assayed in ELISA format using a GST fusion of the N-terminus of Histone H3 as substrate. Plates were coated with substrate, and the...More data for this Ligand-Target Pair