BDBM3184 2-{[2,6-dihydroxy-4-({[(3R,4R)-3-[(4-hydroxybenzene)amido]-1-[(4-methylbenzene)sulfonyl]azepan-4-yl]oxy}carbonyl)phenyl]carbonyl}-3-hydroxybenzoic acid::Balanol Analog 42

SMILES Cc1ccc(cc1)S(=O)(=O)N1CCC[C@@H](OC(=O)c2cc(O)c(C(=O)c3c(O)cccc3C(O)=O)c(O)c2)[C@@H](C1)NC(=O)c1ccc(O)cc1

InChI Key InChIKey=HYMQDYSTAVHSCZ-VAVYLYDRSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 3184   

TargetProtein kinase C alpha type(Homo sapiens (Human))
Sphinx Laboratories

LigandPNGBDBM3184(2-{[2,6-dihydroxy-4-({[(3R,4R)-3-[(4-hydroxybenzen...)
Affinity DataIC50:  6.10E+3nMpH: 7.5 T: 2°CAssay Description:PKC was assayed by quantitating the incorporation of 32P from [gamma-32P]ATP into histone type IIIs.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProtein kinase C beta type(Homo sapiens (Human))
Sphinx Laboratories

LigandPNGBDBM3184(2-{[2,6-dihydroxy-4-({[(3R,4R)-3-[(4-hydroxybenzen...)
Affinity DataIC50:  70nMpH: 7.5 T: 2°CAssay Description:PKC was assayed by quantitating the incorporation of 32P from [gamma-32P]ATP into histone type IIIs.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProtein kinase C beta type(Homo sapiens (Human))
Sphinx Laboratories

LigandPNGBDBM3184(2-{[2,6-dihydroxy-4-({[(3R,4R)-3-[(4-hydroxybenzen...)
Affinity DataIC50:  20nMpH: 7.5 T: 2°CAssay Description:PKC was assayed by quantitating the incorporation of 32P from [gamma-32P]ATP into histone type IIIs.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Bos taurus (bovine))
Sphinx Laboratories

LigandPNGBDBM3184(2-{[2,6-dihydroxy-4-({[(3R,4R)-3-[(4-hydroxybenzen...)
Affinity DataIC50: >1.50E+5nMAssay Description:The activity of PKA, activated by cAMP, is measured by its ability to transfer phosphate from [gamma-32P]ATP to histone.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProtein kinase C delta type(Homo sapiens (Human))
Sphinx Laboratories

LigandPNGBDBM3184(2-{[2,6-dihydroxy-4-({[(3R,4R)-3-[(4-hydroxybenzen...)
Affinity DataIC50:  4.20E+3nMpH: 7.5 T: 2°CAssay Description:PKC was assayed by quantitating the incorporation of 32P from [gamma-32P]ATP into histone type IIIs.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProtein kinase C epsilon type(Homo sapiens (Human))
Sphinx Laboratories

LigandPNGBDBM3184(2-{[2,6-dihydroxy-4-({[(3R,4R)-3-[(4-hydroxybenzen...)
Affinity DataIC50:  1.50E+4nMpH: 7.5 T: 2°CAssay Description:PKC was assayed by quantitating the incorporation of 32P from [gamma-32P]ATP into histone type IIIs.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProtein kinase C eta type(Homo sapiens (Human))
Sphinx Laboratories

LigandPNGBDBM3184(2-{[2,6-dihydroxy-4-({[(3R,4R)-3-[(4-hydroxybenzen...)
Affinity DataIC50:  800nMAssay Description:PKC was assayed by quantitating the incorporation of 32P from [gamma-32P]ATP into histone type IIIs.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProtein kinase C gamma type(Homo sapiens (Human))
Sphinx Laboratories

LigandPNGBDBM3184(2-{[2,6-dihydroxy-4-({[(3R,4R)-3-[(4-hydroxybenzen...)
Affinity DataIC50:  3.50E+3nMpH: 7.5 T: 2°CAssay Description:PKC was assayed by quantitating the incorporation of 32P from [gamma-32P]ATP into histone type IIIs.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed