BDBM318443 NSC332398::US9624235, Compound 1
SMILES C\C(=N/Nc1cc(C)nc2cc3OCOc3cc12)c1cn(C)n(-c2ccccc2)c1=O
InChI Key InChIKey=HRKIWEVPYGRBLN-MFKUBSTISA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 318443
TargetDNA-(apurinic or apyrimidinic site) endonuclease(Homo sapiens (Human))
University of Pittsburgh
US Patent
University of Pittsburgh
US Patent
Affinity DataKi: 180nMAssay Description:The initial screen was designed to look at the effect of potential inhibitors on APE1 repair kinetics. The approach can be used as a high throughput ...More data for this Ligand-Target Pair
TargetDNA-(apurinic or apyrimidinic site) endonuclease(Homo sapiens (Human))
University of Pittsburgh
US Patent
University of Pittsburgh
US Patent
Affinity DataIC50: 4.40E+3nMAssay Description:Inhibition of recombinant His-6 tagged human APE1 expressed in Escherichia coli C41(DE3) using 5'-(F)-CGACTXTTGAATTGACACGCCATGTCGATCAATTCAATAGTCG-(D)...More data for this Ligand-Target Pair
TargetDNA-(apurinic or apyrimidinic site) endonuclease(Homo sapiens (Human))
University of Pittsburgh
US Patent
University of Pittsburgh
US Patent
Affinity DataIC50: 4.40E+3nMAssay Description:The initial screen was designed to look at the effect of potential inhibitors on APE1 repair kinetics. The approach can be used as a high throughput ...More data for this Ligand-Target Pair