BDBM318444 NSC332384::US9624235, Compound 2

SMILES COc1cccc(\C=N\Nc2cc(C)nc3cc4OCOc4cc23)c1

InChI Key InChIKey=MSEAFZSETBWEAL-KEBDBYFISA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 318444   

TargetDNA-(apurinic or apyrimidinic site) endonuclease(Homo sapiens (Human))
University of Pittsburgh

US Patent
LigandPNGBDBM318444(NSC332384 | US9624235, Compound 2)
Affinity DataKi:  220nMAssay Description:The initial screen was designed to look at the effect of potential inhibitors on APE1 repair kinetics. The approach can be used as a high throughput ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDNA-(apurinic or apyrimidinic site) endonuclease(Homo sapiens (Human))
University of Pittsburgh

US Patent
LigandPNGBDBM318444(NSC332384 | US9624235, Compound 2)
Affinity DataIC50:  1.01E+4nMAssay Description:The initial screen was designed to look at the effect of potential inhibitors on APE1 repair kinetics. The approach can be used as a high throughput ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent