BDBM31859 2,4-Bisanilinopyrimidine, 24

SMILES Oc1ccc(Nc2ncc(c(Nc3ccc(O)cc3)n2)C(F)(F)F)cc1

InChI Key InChIKey=YPKCSJRUMZSEIB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 31859   

TargetAurora kinase A(Homo sapiens (Human))
Genentech

LigandPNGBDBM31859(2,4-Bisanilinopyrimidine, 24)
Affinity DataIC50:  14nMAssay Description:Aurora kinase was assayed in ELISA format using a GST fusion of the N-terminus of Histone H3 as substrate. Plates were coated with substrate, and the...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed