BDBM31863 2,4-Bisanilinopyrimidine, 29

SMILES COc1ccccc1Nc1nc(Nc2ccc(O)cc2)ncc1F

InChI Key InChIKey=LZJBAIBBCDYVPK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 31863   

TargetAurora kinase A(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM31863(2,4-Bisanilinopyrimidine, 29)
Affinity DataIC50:  20nMAssay Description:Inhibition of AurA expressed in Escherichia coli or baculovirus-infected insect cells by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM31863(2,4-Bisanilinopyrimidine, 29)
Affinity DataIC50:  20nMAssay Description:Aurora kinase was assayed in ELISA format using a GST fusion of the N-terminus of Histone H3 as substrate. Plates were coated with substrate, and the...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed