BDBM31870 2,4-Bisanilinopyrimidine, 36

SMILES CN(C)C(=O)c1ccc(Nc2nc(Nc3ccc(O)cc3)ncc2F)cc1

InChI Key InChIKey=CGRAHNALUOBLKM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 31870   

TargetAurora kinase A(Homo sapiens (Human))
Genentech

LigandPNGBDBM31870(2,4-Bisanilinopyrimidine, 36)
Affinity DataIC50:  640nMAssay Description:Aurora kinase was assayed in ELISA format using a GST fusion of the N-terminus of Histone H3 as substrate. Plates were coated with substrate, and the...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed